DNA replication in eukaryotes is a highly orchestrated process that ensures precise genome duplication before cell division. Initiation occurs at multiple replication origins that are licensed in G1 ...
Archaeal DNA replication combines features of bacterial and eukaryotic systems within a unique framework adapted to extreme environments and diverse genome architectures. Initiation typically occurs ...
An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived ...