Human cells are organized across a spatial hierarchy of components, ranging from small protein complexes at the scale of nanometres to large condensates, compartments and organelles at the scale of ...

Methodological developments in biomedical research are currently moving towards single-cell approaches. This allows for a much better spatial and functional characterization of, for example, the ...

Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of ...

Biomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to change the function of different cells in ...

Both images show individual red blood cells. The one on the right, produced by STED, more clearly shows the Piezo1 proteins (in green), which are a mechanical calcium channel and play a crucial role ...

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...

Engineered fluorescent nanobodies that work inside living cells can label multiple proteins in different colors at once, ...

A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand how RNA works. The method, published in Molecular Cell, is a powerful ...

That means researchers can now use it to better understand how genes function, how diseases start and how to design better treatments. "Every single cell can have a different chromosome structure," ...

Introduction Sjögren’s disease (SjD) is a systemic, rheumatic autoimmune disorder evidenced by broad organ-specific ...

In each cell of your body, DNA is stored in structures called chromosomes. When cells divide, these chromosomes are copied, ...