Scale-up involves increasing pump sizes, reactor volumes, and flow rates—but the process control logic and system ...

ISA106 started with the goal of developing standards, recommended practices, and technical reports on the design and implementation of procedures for automating continuous process operations. The ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...

Methods to Simultaneously Reduce Bioburden and Maintain Column Integrity, Explained Continuous bioprocessing is inevitably becoming the future of biomanufacturing. To date, several steps within a ...

Anything that you do well is worth doing better over time. The term "continuous improvement" describes a process practiced by quality engineers but it speaks to something that every conscientious ...

Continuous manufacturing and a quality-by-design development approach are a natural fit. FDA, as well as other regulatory agencies around the world, have for many years been encouraging drug makers to ...

Continuous process environments tend to be stable — until they’re not. When that happens, the consequences can be catastrophic. Continuous process environments tend to be stable — until they’re not.

Across industries such as food processing, pulp and paper, ceramics, engineered wood, biomass, and chemicals, manufacturers ...

In November 2016, Continuus Pharmaceuticals was awarded a $4.4 million contract by the U.S. Food and Drug Administration (FDA). The partnership revolves around a pilot project that will result in a ...