Dysregulated DNA replication is a cause and a consequence of aneuploidy in cancer, yet the interplay between copy number alterations (CNAs), replication timing (RT) and cell cycle dynamics remain ...
In a human cell, thousands of replication forks simultaneously coordinate duplication of the entire genome. The rate at which this process occurs might depend on the epigenetic state of the genome and ...
Protecting essential data has never been more important than it is today due to the escalating cost of system downtime and the increased likelihood of natural and human-made disasters. As a result, ...