The nucleotide excision repair (NER) mechanism is responsible for removing bulky DNA damage, such as pyrimidine dimers induced by ultraviolet (UV) light. The NER pathway excises the damaged strand ...
Methyleugenol (ME) is a hepatotoxic phenylpropene naturally present in various herbs and spices. Following dietary exposure, ME undergoes metabolic activation in the liver, resulting in the formation ...
The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...
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