A direct gene transfer into defined sites on chromosomes has the potential for both elucidating the molecular mechanisms underlying genome function and for developing clinical applications such as ...

Murine leukemia virus (MLV)-based vectors are still the most frequently used gene delivery vehicles, employed in almost 40% of approved clinical protocols worldwide. 1,2 Despite their frequent use as ...

The baculovirus expression vector system (BEVS) provides a versatile platform for the expression of individual recombinant proteins as well as multimeric protein complexes, virus-like particles, ...

A universal vector (IL-60 and auxiliary constructs), expressing or silencing genes in every plant tested to date, is described. Plants that have been successfully manipulated by the IL-60 system ...

Recombinant protein expression is an essential pillar of biomedical research. Efforts from enzyme discovery to protein structure-function study to development of drugs and biological therapeutics all ...