A group of researchers at University of California San Diego School of Medicine led an investigation that offers new insight into the development of the human forebrain. The study, led by Changuk ...

The p53 gene is a key regulator of cell apoptosis. It has been suggested that p53 function is involved in cell death in stroke. p53 immunoreactivity has been detected in brain tissue derived from ...

The brain regulates physiological functions integral to survival. However, the insight into brain neuronal regulation of peripheral immune function and the neuromediator systems and pathways involved ...

Department of Cognitive Science, University of California, San Diego, San Diego, CA, USA Cortically projecting basal forebrain neurons play a critical role in learning and attention, and their ...

The forebrain is required for generating mammalian voluntary and innate behaviors. Multiresolution consensus cluster analysis generated a panoramic, hierarchical view of rat intraforebrain ...

Early-onset familial Alzheimer's disease is the most aggressive form of Alzheimer's, striking patients as early as their 30s; those patients typically carry mutations in presenilin-1 and presenilin-2.

Zhao et al. report valuable adverse effects on cell proliferation, differentiation and gene expression, possibly linked to reduced binding activity of the transcription factor GTF2IRD1 to the ...

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