In May 2025, President Donald Trump signed an executive order to restrict research on viruses and pathogens called gain-of-function studies. The National Institutes of Health is now taking steps to ...

Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a ...

Activists want it banned. The US government may soon further restrict it. And politicians won’t stop talking about it. So-called “gain-of-function” pathogen research has faced growing scrutiny ever ...

Due to unanswered questions into the origins of the coronavirus pandemic, both the U.S. government and scientists have called for a deeper examination into the validity of claims that a virus could ...

Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposium on Gain of Function (GOF) research. Convened in December 2014 by the National Research Council ...