Nature

Insulin-Like Growth Factor Modulation in Cancer and Muscle Systems

The insulin-like growth factor (IGF) axis exerts a central role in coordinating cellular growth, survival and differentiation across diverse tissues. IGF-1, produced as multiple prohormone isoforms ...
Mathrubhumi English

Tesamorelin: Molecular signaling, metabolic modulation and emerging research

Explore tesamorelin's molecular signalling pathways, metabolic effects and emerging research developments, including its role ...
ascopubs.org

Growth modulation index and RECIST-based STBSG-EORTC criteria for the assessment of drug activity in advanced soft tissue sarcoma (ASTS) patients (pts).

Growth modulation index (GMI) as a metric of clinical benefit assessment among advanced soft tissue sarcoma (ASTS) patients receiving trabectedin as salvage therapy. This is an ASCO Meeting Abstract ...
ascopubs.org

Growth modulation index (GMI) as a metric of clinical benefit assessment among advanced soft tissue sarcoma (ASTS) patients receiving trabectedin as salvage therapy.

18f-FDG-PET imaging as an early survival predictor in patients with high-grade soft tissue sarcomas undergoing neoadjuvant therapy. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I ...
Nature

Myostatin Modulation in Skeletal Muscle Development

Myostatin, a member of the transforming growth factor-β superfamily, is a principal negative regulator of skeletal muscle growth and homeostasis. By binding to activin type II receptors, myostatin ...