Peptidyl-arginine deiminase 2 (PAD2) enzyme converts arginine amino acid residues in histone proteins into citrulline groups and promotes tumor cell proliferation in pancreatic ductal adenocarcinoma, ...

Histone modifications constitute a dynamic layer of epigenetic regulation that shapes gene expression programmes central to fungal virulence, morphogenesis and drug resistance. In pathogenic fungi ...

Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. In the presence of HBx, histone-modifying factors such as p300/CBP, Set1A, ...

While each cell contains the complete genetic blueprint of an organism, chemical marks on the DNA—so-called epigenetic modifications—control which genes are active when and where. A team led by ...