What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases.

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or small cells grow across multiple tissues.

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Researchers uncover a cunning new trick by which breast cancer cells evade immune attack. While the cGAS-STING pathway normally detects cytosolic DNA and activates anti-tumor immunity via ...

Originally classified as ‘junk DNA’, genomic regions which are transcribed into RNAs that do not serve as template for protein production have attracted increasing attention in the last two decades.

These genes are part of the non-coding genome, which makes up about 98% of our DNA and was long dismissed as “junk.” This new ...

Swiss start-up Haya Therapeutics has formed a partnership with Eli Lilly – worth up to $1 billion – to look for new therapies for obesity in non-coding DNA. The biotech focuses on trawling the 98% of ...