A systematic investigation into the etiology of congenital heart diseases (CHD) has been undertaken through the testing of four alternative hypotheses. Data was obtained for six common congenital ...

One hundred families ascertained through a proband's having atrial septal defect (ostium secundum) were studied. Selection of certain pedigrees from the overall data could lead to the conclusion that ...

This study is led by Prof. Hongyan Wang (Institute of Reproduction and Development, Obstetrics and Gynecology Hospital, Institute of Metabolism and Integrative Biology, Fudan University), Prof. Qihua ...

Here, we give a historical overview of the search for genetic variants that influence the susceptibility of an individual to a chronic disease, from RA Fisher's seminal work to the current excitement ...