Brain volume and function are altered in individuals with opioid use disorder, a new Yale study finds. Using magnetic resonance imaging (MRI) and functional MRI (fMRI), researchers observed the ...

The opioid crisis refers to the rapid increase in opioid overuse, misuse, and overdose deaths since the 1990s. It involves both prescription opioids and opioids that people use recreationally. People ...

Opioids slot into opioid receptors and activate them. This sends signals to your brain to relieve pain and promote pleasure. Both endogenous opioids, which your body naturally produces, and exogenous ...

Researchers at the Yale School of Medicine found structural and functional alterations in specific brain regions of individuals with opioid use disorder. The study's results were published today in ...

Opioid use disorder (OUD) is a serious condition. People with OUD may have several distinct types of symptoms that can affect behavior, physical health, and mental health. Opioid use disorder (OUD) is ...

Opioid cross-reactivity is the uncommon occurrence of having an allergic reaction to more than one opioid. Allergies to opioids present a unique challenge in pain management due to the limited ...

Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States’ fight against the opioid crisis. It reverses an opioid overdose nearly instantly, restarting ...

This study investigated how geography helps explain the striking increase in opioid-related overdose deaths among Black Americans since the proliferation of fentanyl. Using mortality data from the ...

Articles in this report were published with editorial independence. The collection was made possible by the support of WVU Rockefeller Neuroscience Institute. On June 11, 2018, seeking relief from ...

The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some ...