Researchers at the University of Cologne's Center for Molecular Medicine Cologne (CMMC) have discovered a previously unknown ...

A team of researchers at the University of Cologne's Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

KRAS‑mutant pancreatic cancer relies on caspase‑8 to evade necroptosis, according to a new study in preclinical models.

The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved in programmed cell death (PCD) play a key role in normal tissue renewal and ...

How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from the fields of physics, chemistry and medicine at Heinrich Heine University ...

Programmed cell death encompasses several regulated pathways—apoptosis, necroptosis, pyroptosis, autophagy-related cell death and ferroptosis—that maintain tissue homeostasis and serve as intrinsic ...

Efficacy of nivolumab/ipilimumab as first-line treatment of pleural mesothelioma in the German real-world setting. Outcome of chemo-immunotherapy for extensive-stage small-cell lung cancer according ...

This finding, he suggests, helps link the study of cell death in the worm and oncogenesis in people. "There were a number of papers that had suggested a relationship between cell death and oncogenesis ...

Risk of non-small cell lung cancer (NSCLC), a malignancy that develops in the tissues of the lung, increases considerably ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...