Now he has a company that is trying to change the way we think about the so-called dark genome or noncoding DNA. Previously ...

Direct reprogramming, inducing the conversion of one type of somatic cell into another by the forced expression of defined transcription factors, is a technology with anticipated medical applications.

During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.

Mesenchymal stromal cells (MSCs), also termed mesenchymal stem cells in the literature, have long been proposed for use in regenerative medicine and cell therapy. Currently, their therapeutic effects ...

Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

A new study developed a mineralized DNA hydrogel that combines immune regulation with sustained bone regeneration. Using ...

In a recent study posted to the bioRxiv* preprint server, researchers performed age-reversing experiments, in vivo and in vitro, in progeroid mice using gene therapy. Study: Gene Therapy Mediated ...

Researchers have attained the holy grail of cellular reprogramming: inducing pluripotency without using any DNA-based materials. Using only a cocktail of purified proteins and a chemical additive, ...

Researchers at Johns Hopkins University and Texas A&M University have documented at least 522 autosomal sites where DNA ...