Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

Full view of how bones and joints form in the first trimester uncovers cells and pathways that could help diagnose and treat skeletal conditions in the future. The first 'blueprint' of human skeletal ...

In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities, including a reduction in the self-renewal and differentiation abilities of mesenchymal stem cells, an ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Researchers at the University of Alberta have fine-tuned a process for creating accurate digital 3D reconstructions of human bones, offering students and researchers a cost-effective and accessible ...

Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

New publication outlines the stakeholder-driven, evidence-based process behind a global, multilingual platform for people living with osteoporosis and their caregivers. A new paper published in ...