New human research reveals how gut bacteria and creatine may restore brain energy and improve depression. If you have or know ...

A clinical trial led by St. Michael's Hospital researchers found that using nerve blocks, an anesthesia technique to numb ...

The trial is real, and it is a meaningful step. It is also, by design, small, tightly controlled, and years away from ...

An artificial intelligence system that operates like a collaborative team of medical experts could accelerate clinical trial design, one of the most difficult steps in drug development, according to a ...

Malaria control and elimination is threatened by the spread of insecticide resistance and behavioral adaptation of vectors. Whether mass administration of ivermectin, a broad-spectrum antiparasitic ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

Impact of Lean Body Mass–Based Oxaliplatin Dose Calculation on Neurotoxicity in Adjuvant Treatment of Stage III Colon Cancer: Results of the Phase II Randomized LEANOX Trial The trials were conducted ...

Delgocitinib tripled week-16 treatment success versus placebo (RR 3.17), yielding an absolute 16.9% benefit and NNT of 6. Early separation by week 4 supports adherence, with sustained superiority at ...

Timing of Adjuvant Chemotherapy After Gastrectomy in Patients With Stage II to III Gastric Cancer: A Target Trial Emulation Study Master protocols represent transformations, enabling multiple ...