A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various ...

A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA ...

mRNA vaccines work by delivering genetic instructions into cells, but a new study shows that which cells express the mRNA can alter the resulting immune response. A new study in Nature Biotechnology ...

Ambient-stable microneedle patches are positioned as a route to reduce refrigeration dependence and simplify administration ...

South Korean researchers have, for the first time in the world, uncovered how messenger ribonucleic acid (mRNA) vaccines enter human cells, function inside the body, and are blocked by certain ...

An AI-identified lipid called P1 delivered mRNA 14.8 times more efficiently than the clinically approved lipid ALC-0315. Lipid P1's unique three-dimensional conformation allows it to bind ...

In two experiments, researchers have found that introducing people to "mental models" about how mRNA vaccination works and how the body protects itself from foreign DNA can preemptively or reactively ...

LNP–mRNA drug products are produced by mixing the nucleic acid drug substance with various lipid components, such as phospholipids, cholesterol, PEG–lipids and ionizable lipids, resulting in a ...

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov ...